- 英文名称
- Bictegravir Sodium
- 分子式
- C21H17F3N3NaO5
- 分子量
- 471.36
- 中文别名
- (2R,5S,13aR)-8-羟基-7,9-二氧代-N-(2,4,6-三氟苄基)-2,3,4,5,7,9,13,13a-八氢-2,5-甲桥吡啶并[1',2':4,5]吡嗪[2,1-b][1,3]氧氮杂卓-10-甲酰胺钠盐; 比卡格韦纳; 比格特韦钠盐; 比克替拉韦钠; 比特格韦钠; 比格卡韦; (2R,5S,13aR)-8-Hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide sodium salt; GS-9883; GS-9883-01; GS-9883 Sodium; Bicagrevir; Bicagrevir sodium; Bikagwena; Bictegravir Sodium Salt; Sodium (1S,11R,13R)-3,6-dioxo-7-[(2,4,6-trifluorobenzyl)carbamoyl]-12-oxa-2,9-diazatetracyclo[11.2.1.02,11.04,9]hexadeca-4,7-dien-5-olate; (2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide monosodium salt
- 用途
- 作为抗艾滋病新药比卡格韦（Bictegravir,BIC）的成分之一，用于成人HIV-1感染者初始治疗，或经治患者替换方案；BIC是HIV-1整合酶抑制剂，必妥维（比克恩丙诺片）为三合一复方单片制剂，具有强效病毒抑制、耐药屏障高、长期安全性好等特点。
