- 英文名称
- Olitigaltin
- 分子式
- C28H30F2N6O8S
- 分子量
- 648.64
- 中文别名
- (2R,2'R,3R,3'R,4S,4'S,5R,5'R,6S,6'S)-6,6'-硫基双(4-(4-(3-氟苯基)-1H-1,2,3-三唑-1-基)-2-(羟甲基)四氢-2H-吡喃-3,5-二醇); 化合物TD139; (2R,2'R,3R,3'R,4S,4'S,5R,5'R,6S,6'S)-6,6'-硫代双(4-(4-(3-氟苯基)-1H-1,2,3-三唑-1-基)-2-(羟甲基)四氢-2H-吡喃-3,5-二醇); TD139; TD-139; TD 139; GB0139; GB-0139; 3-Deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-β-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-β-D-galactopyranoside; Gal-3 Inhibitor GB0139; Galectin-3 Inhibitor GB-0139; Olitigaltina; Olitigaltine; bis-(3-deoxy-3-(3-fluorophenyl-1h-1,2,3-triazol-1-yl)-beta-d-galactopyranosyl)-sulfane; 3,3'-DIDEOXY-3,3'-BIS-(4-(3-FLUOROPHENYL)-1H-1,2,3-TRIAZOL-1-YL)-1,1'-SULFANEDIYL-DI-β-D-GALACTOPYRANOSIDE; BIS(3-DEOXY-3-(3-FLUOROPHENYL-1H-1,2,3-TRIAZOL-1-YL)-β-D-GALACTOPYRANOSYL)SULFANE; 33DFTG
- 用途
- 化学合成；作为有效的、具有选择性的galectin-3抑制剂，Kd值为0.036 µM，用于特发性肺纤维化（IPF）的治疗，靶点为galectin-3、galectin-1、galectin-7
