- 英文名称
- Ganciclovir-d5
- 分子式
- C9H8D5N5O4
- 分子量
- 260.26
- 中文别名
- [2H5]-更昔洛韦; 氘5-更昔洛韦; 2-Amino-9-(((1,3-dihydroxypropan-2-yl-1,1,2,3,3-d5)oxy)methyl)-3,9-dihydro-6H-purin-6-one; 2-amino-9-[(1,1,2,3,3-pentadeuterio-1,3-dihydroxypropan-2-yl)oxymethyl]-3H-purin-6-one; Ganguard-d5; Vitrasert-d5; Biolf 62-d5; Denosine-d5; Ganquard-d5; Hydroxyacyclovir-d5; Gancyclovir-d5; Natclovir-d5; 2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]6H-purin-6-one-d5; 2-AMino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxyMethyl)ethoxy-d5]Methyl]-6H-purin-6-one; 2'-NDG-d5; 2'-Nor-2'-deoxyguanosine-d5; 9-(1,3-Dihydroxy-2-propoxyMethyl)guanine-d5; BW 759-d5; 2-amino-9-[(1,1,2,3,3-pentadeuterio-1,3-dihydroxypropan-2-yl)oxymethyl]-1H-purin-6-one; 2-Amino-9-({[1,3-dihydroxy(~2~H_5_)propan-2-yl]oxy}methyl)-3,9-dihydro-6H-purin-6-one; 2-Amino-9-[[(1,3-dihydroxy-2-propyl-1,1,2,3,3-d5)oxy]methyl]-1H-purin-6(9H)-one
- 用途
- 示踪分析试剂；2-氨基-1,9-[[2-羟基-1-(羟甲基)乙氧基]甲基]-6H-是Ganciclovir的氘代物，Ganciclovir是核苷类似物和口服抗病毒活性分子，对CMV具有抗病毒活性，在体外对疱疹病毒和其他一些DNA病毒也具有抗病毒活性，抑制人类疱疹病毒（HSV 1型和2型，CMV）和腺病毒血清型等的体外复制，对猫1型疱疹病毒（FHV-1）的IC50为5.2 μM。
