- 英文名称
- Coronarin D methyl ether
- 分子式
- C21H32O3
- 分子量
- 332.5
- 中文别名
- 狗牙花碱 D 甲醚; Methoxycoronarin D; (3E)-3-[2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-5-methoxyoxolan-2-one; (3E)-3-[[(1S,4aS,8aS)-Decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]methylene]dihydro-5-methoxy-2(3H)-furanone; 2(3H)-Furanone,3-[[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]methylene]dihydro-5-methoxy-,(3E)-; (3E)-5-Methoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone; (3Z)-5-Methoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone; (E)-5-Methoxy-3-(2-((1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydronaphthalen-1-yl)ethylidene)dihydrofuran-2(3H)-one
- 用途
- Methoxycoronarin D 可以从 Hedychium coronarium J. Koenig 中分离得到，是一种 NF-κB有效抑制剂，IC50 值为 7.3 μM。Methoxycoronarin D 还是一种 COX-1的选择性抑制剂，IC50 值为 0.9 μM。
