- 英文名称
- N1,N7-Bis(1,2,3,4-tetrahydroacridin-9-yl)heptane-1,7-diamine dihydrochloride
- 分子式
- C33H42Cl2N4
- 分子量
- 565.62
- 中文别名
- bis(7)-Tacrine; 化合物bis(7)-Tacrine; 化合物 T22048; bis(7)-Tacrine; N,N'-bis(1,2,3,4-tetrahydroacridin-9-yl)heptane-1,7-diamine,dihydrochloride; N,N'-Di(1,2,3,4-tetrahydro-9-acridinyl)-1,7-heptanediamine dihydrochloride; 9-Amino-1,2,3,4-tetrahydroacridine bis 1,7-heptylene dihydrochloride; Tacrine-Based Inhibitor 2f; heptylene-bis(tacrine) dihydrochloride; heptylene-bis(THA) dihydrochloride; 1,7-Heptanediamine, N,N-bis(1,2,3,4-tetrahydro-9-acridinyl)-, hydrochloride (1:2); N,N'-Di-1,2,3,4-Tetrahydroacridin-9-Ylheptane-1,7-Diamine; bis(7)-cognitin; Bis-7-Tacrine; Heptylenebis-tacrine; heptylene-bis(tacrine); bis(7)-tetrahydroaminacrine; N,N'-bis(1,2,3,4-tetrahydro-9-acridinyl)-1,7-heptanediamine, dihydrochloride; Bis(heptyl)-cognitin dihydrochloride
- 用途
- 生命科学；Bis(7)-tacrine dihydrochloride是从tacrine中提取的二聚体乙酰胆碱酯酶(AChE)抑制剂，通过阻断NMDA受体防止谷氨酸诱导的神经元凋亡，是有效的GABAA受体拮抗剂，有潜能用于阿尔茨海默病的研究。
