- 英文名称
- Mesaconine
- 分子式
- C24H39NO9
- 分子量
- 485.57
- 中文别名
- 中乌头原碱; (3R,4R,6S,6aS,7R,7aR,8R,9R,10S,11S,11aR,12R,12aR,13R,14S)-6,10,13-三甲氧基-3-(甲氧基甲基)-1-甲基十二氢-11aH-3,6a,12-(环乙烷[1,1,2]三基)-7,9-甲桥萘并[2,3-b]氮杂环辛烷-4,8,9,11,11a(7H)-戊醇; (3R,4R,6S,6aS,7R,7aR,8R,9R,10S,11S,11aR,12R,12aR,13R,14S)-6,10,13-Trimethoxy-3-(methoxymethyl)-1-methyldodecahydro-11aH-3,6a,12-(epiethane[1,1,2]triyl)-7,9-methanonaphtho[2,3-b]azocine-4,8,9,11,11a(7H)-pentaol; 1,6,16-Trimethoxy-4-(methoxymethyl)-20-methylaconitane-3,8,13,14,15-pentol; (15S,16S)-1α,6α,16-Trimethoxy-4-methoxymethyl-20-methyl-aconitan-3α,8,13,14α,15-pentaol; (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-1,6,16-Trimethoxy-4-(methoxymethyl)-20-methyl-aconitane-3,8,13,14,15-pentol; Aconitane-3,8,13,14,15-pentol, 1,6,16-trimethoxy-4-(methoxymethyl)-20-methyl-, (1α,3α,6α,14α,15α,16β)-
- 用途
- 新乌头原碱用于制备预防和/或治疗心肌纤维化及由其引起慢性心衰的药物；具有抑制或逆转心肌组织纤维化、改善心脏异常重构、心功能障碍，提高生存率，对抗心肌组织炎症，抑制心肌细胞凋亡等药理作用，对心血管有作用。
