- 英文名称
- I-BOP
- 分子式
- C23H29IO5
- 分子量
- 512.38
- 中文别名
- (5Z)-7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-羟基-4-(4-碘苯氧基)-1-丁烯-1-基]-7-氧杂环[2.2.1]庚-2-基]-5-庚烯酸; (Z)-7-((1S,2S,3R,4R)-3-((R,E)-3-Hydroxy-4-(4-iodophenoxy)but-1-en-1-yl)-7-oxabicyclo[2.2.1]heptan-2-yl)hept-5-enoic acid; 7-[(1s,2r,3r,4r)-3-[(1e,3r)-3-hydroxy-4-(4-iodophenoxy)-1-butenyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5z-heptenoic acid; (5Z)-7-{(1S,2R,3R,4R)-3-[(1E,3R)-3-Hydroxy-4-(4-iodophenoxy)-1-buten-1-yl]-7-oxabicyclo[2.2.1]hept-2-yl}-5-heptenoic acid; (Z)-7-[(1S,4R,5R,6R)-5-[(E,3R)-3-hydroxy-4-(4-iodophenoxy)but-1-enyl]-7-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoic acid; (Z)-7-((1S,4R,5R,6R)-5-((E,3R)-3-hydroxy-4-(4-iodophenoxy)but-1-enyl)-7-oxabicyclo(2.2.1)heptan-6-yl)hept-5-enoic acid; (1S-(1alpha,2alpha(Z),3beta(1E,3S*),4alpha))-7-(3-(3-Hydroxy-4-(4-iodophenoxy)-1-butenyl)-7-oxabicyclo[2.2.1]hept-2-yl)-5-heptenoic acid; [1S-[1.alpha.,2.alpha.(Z),3.beta.(1E,3S*),4.alpha.]]-7-[3-[3-Hydroxy-4-(4-iodophenoxy)-1-butenyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid; (Z)-7-[(1S,2R,3R,4R)-3-[(E,3R)-3-hydroxy-4-(4-iodophenoxy)but-1-enyl]-7-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid; (5Z)-7-[(1S,4R)-3β-[(1E,3R)-3-Hydroxy-4-(p-iodophenoxy)-1-butenyl]-7-oxabicyclo[2.2.1]heptane-2α-yl]-5-heptenoic acid; 5-Heptenoic acid, 7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-hydroxy-4-(4-iodophenoxy)-1-buten-1-yl]-7-oxabicyclo[2.2.1]hept-2-yl]-, (5Z)-
- 用途
- I-BOP是血栓素A2受体(TP)的激动剂，KD为0.61 nM，通过激活血管平滑肌中的PI3K通路促进细胞增殖，剂量依赖性双相影响海马神经元中的兴奋性突触后电位(e.p.s.p.)，用于生命科学领域。
