- 英文名称
- Etrasimod arginine
- 分子式
- C32H40F3N5O5
- 分子量
- 631.69
- 中文别名
- (R)-2-(7-((4-环戊基-3-(三氟甲基)苄基)氧基)-1,2,3,4-四氢环戊并[b]吲哚-3-基)乙酸 (S)-2-氨基-5-胍基戊酸盐(1:1); (R)-2-(7-((4-环戊基-3-(三氟甲基)苄基)氧基)-1,2,3,4-四氢环戊并[B]吲哚-3-基)乙酸(S)-2-氨基-5-胍基戊酸盐; 伊曲莫德-L-精氨酸盐; 伊曲莫得精氨酸盐; (R)-2-(7-((4-Cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid (S)-2-amino-5-guanidinopentanoic acid(1:1); Etrasimod L-Arginine; APD334 L-Arginine; APD-334 L-ARGININE; Velsipity; Etrasimod (arginine); L-arginine mono((3R)-7-((4-cyclopentyl-3-(trifluoromethyl)phenyl)methoxy)-1,2,3,4-tetrahydrocyclopenta(b)indol-3-yl)acetate; L-Arginine, (3R)-7-((4-cyclopentyl-3-(trifluoromethyl)phenyl)methoxy)-1,2,3,4-tetrahydrocyclopent(b)indole-3-acetate (1:1); L-arginine, (3R)-7-[[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy]-1,2,3,4-tetrahydrocyclopent[b]indole-3-acetate (1:1); L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid; L-arginine--[(3R)-7-{[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy}-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]acetic acid (1/1)
- 用途
- 化学合成；Etrasimod arginine 是口服有效的 S1P 受体调节剂，是 S1P1 受体的强效完全激动剂，对 S1P4 具有部分激动活性，可减轻 CD4+CD45RBhigh T 细胞转移小鼠结肠炎模型中的炎症。
