- 英文名称
- 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-((2-(((S)-1-((2-(((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)amino)-2-oxoethyl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-2-oxoethyl)amino)-2-oxoethyl)hexanamide
- 分子式
- C49H51FN8O11
- 分子量
- 946.97
- 中文别名
- MC-GGFG-DX8951; 群司珠单抗杂质1; N-[6-(2,5-二氢-2,5-二氧代-1H-吡咯-1-基)-1-氧代己基]甘氨酰甘氨酰-L-苯丙氨酰-N-[(1S,9S)-9-乙基-5-氟-2,3,9,10,13,15-六氢-9-羟基-4-甲基-10,13-二氧代-1H,12H-苯并[DE]吡喃并[3′,4′:6,7]吲哚嗪并[1,2-B]喹啉-1-基]甘氨酰胺; MC-GGFG-DX8951; MC-GGFG-Exatecan; Trastuzumab Impurity 1; Glycinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl]-; 6-(2,5-dioxopyrrol-1-yl)-N-[2-[[2-[[(2S)-1-[[2-[[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]hexanamide
- 用途
- 作为抗体偶联药物（ADC）的一部分，使用抗肿瘤活性成分伊喜替康（Exatecan），具有抗癌活性。
