- 英文名称
- 4'-C-azido-2'-deoxy-2'-fluoro-beta-D-arabinouridine
- 分子式
- C9H10FN5O5
- 分子量
- 287.2
- 中文别名
- 1-[4-C-叠氮基-2-脱氧-2-氟-BETA-D-阿拉伯呋喃糖基]-2,4(1H,3H)-嘧啶二酮; 阿兹夫定杂质3; 4'-叠氮-2'-脱氧-2'-氟-β-D-阿拉伯呋喃糖基尿嘧啶; 2,4(1H,3H)-PyriMidinedione, 1-[4-C-azido-2-deoxy-2-fluoro-b-D-arabinofuranosyl]-; 4'-Azido-2'-deoxy-2'-fluoro-beta-D-arabino ribofuranosyl uracil; 4'-Azido-2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl uracil; 1-[4-C-Azido-2-deoxy-2-fluoro-beta-D-arabinofuranosyl]-2,4(1H,3H)-pyrimidinedione; 1-[(2R,3S,4R,5R)-5-Azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione; 1-[(2R,3S,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 1-[(2R,3S,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione; Azvudine Impurity 3; 4'-Azido-2'-deoxy-2'-fluoro-beta-D-arabinoribofuranosyluracil; 1-((2R,3S,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-[(2R,3S,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-hydroxy-pyrimidin-2-one
- 用途
- 1-[4-C-叠氮基-2-脱氧-2-氟-β-D-阿拉伯呋喃糖基]-2,4(1H,3H)-嘧啶二酮是尿嘧啶核苷类似物，尿苷类似物可用于研究抗惊厥和抗焦虑活性、开发新型降压剂；作为点击化学试剂，含叠氮基团可与炔基分子发生铜催化叠氮-炔环加成反应（CuAAc），或与DBCO/BCN基团分子发生环张力驱动的炔-叠氮环加成反应（SPAAC）。
