- 英文名称
- Deoxyandrographolide
- 分子式
- C20H30O4
- 分子量
- 334.45
- 中文别名
- 穿心莲甲素; 14-去氧穿心莲内酯; 脱羟基穿心莲内酯; 去氧穿心莲内脂; 3-(2-(4AS,5R,6R,8AR)-6-羟基-5-(羟甲基)-2,5,8A-三甲基-3,4,4A,5,6,7,8,8A-八氢萘-1-基)乙基)呋喃-2(5H)-酮; iso-14-deoxyandrographolide; 3-{2-[(4aS,5R,6R,8aR)-6-Hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]ethyl}furan-2(5H)-one; 3-{2-[(4aS,5R,6R,8aR)-6-Hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahydro-1-naphthalenyl]ethyl}-2(5H)-furanone; ANDROGRAPHOLIDE, DEOXY-; 4-[2-[(4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,6,7,8-hexahydronaphthalen-1-yl]ethyl]-2H-furan-5-one; 2(5H)-Furanone, 3-[2-[(4aS,5R,6R,8aR)-3,4,4a,5,6,7,8,8a-octahydro-6-hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-1-naphthalenyl]ethyl]-; 3-[2-[(4aS,5R,6R,8aR)-3,4,4a,5,6,7,8,8a-Octahydro-6-hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-1-naphthalenyl]ethyl]-2(5H)-furanone; 3-(2-((4aS,5R,6R,8aR)-6-Hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)ethyl)furan-2(5H)-one
- 用途
- 化学合成；用于含量测定/鉴定/药理实验等；具有解热、抗炎、抗钩端螺旋体病、抗菌、抗癌、保肝作用和抗高血压等活性；可抑制LPS诱导的iNOS mRNA水平升高及促炎症介质TNF-α和IL-6的产生；增强NGF诱导的神经突起生长；临床试用治疗钩端螺旋体、急性细菌性痢疾、上呼吸道感染、流行性感冒及原因不明的发热等病症均有一定疗效；能减少二甲苯或H+刺激所致伊文思兰自毛血管壁的渗出，有抑制巴豆油所致大鼠炎性渗出作用，对大鼠蛋清性足肿显著抑制作用，对肾上腺皮质功能有不同程度的兴奋作用
