- 英文名称
- 25-Hydroxyvitamin D2
- 分子式
- C28H44O2
- 分子量
- 412.65
- 中文别名
- 25-羟基维他命D2; 25-羟基麦角甾醇; 25-羟麦角甾醇; (S,Z)-3-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-羟基-5,6-二甲基庚-3-烯-2-基)-7a-甲基八氢-4H-茚-4-亚基)亚乙基)-4-亚甲基环己-1-醇; 25-Hydroxyergocalciferol; 25-hydroxycalciferol; Ercalcidiol; (S,Z)-3-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexan-1-ol; (3S,5Z,7E,20R,22E)-9,10-Secoergosta-5,7,10,22-tetraene-3,25-diol; 9,10-Secoergosta-5,7,10(19),22-tetraene-3,25-diol; 9,10-Secoergosta-5,7,10(19),22-tetraene-3β,25-diol
- 用途
- Ercalcidiol is a vitamin D2 metabolite used as a vitamin D nutritional status indicator. Differentiation between Ercalcidiol (25(OH)D₂) and 25(OH)D₃ is important for monitoring vitamin D therapy, as vitamin D₂ is the predominant prescription form. Ercalcidiol has a shorter half-life and binds less well to the vitamin D binding protein, making it less potent and requiring higher doses than vitamin D₃. Some assays have diminished capacity to detect Ercalcidiol, risking dangerous overdosing when monitoring vitamin D₂ therapy.
