- 英文名称
- Cevimeline
- 分子式
- C10H17NOS
- 分子量
- 199.31
- 中文别名
- 顺式-2-甲基-1'-氮杂螺[[1,3]氧硫杂戊烷-5,3'-双环[2.2.2]辛烷]; cis-2-Methyl-1'-azaspiro[[1,3]oxathiolane-5,3'-bicyclo[2.2.2]octane]; cevimelina; cevimelinum; Sni 2011; 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine; (2R)-5'-methyl-4-azaspiro[bicyclo[2.2.2]octane-2,2'-[1,4]oxathiolane]; (2R)-5'-methyl-4-azaspiro(bicyclo(2.2.2)octane-2,2'-(1,4)oxathiolane); Spiro(1-azabicyclo[2.2.2]octane-3,5'-(1,3)-oxathiolane), 2'-methyl-, (2'R,3R)-rel-; Spiro(1-azabicyclo[2.2.2]octane-3,5'-(1,3)-oxathiolane), 2'-methyl-, cis-; (2R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]; Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-, (2'R,3R)-rel-; rel-(+)-(2a(2)R,3R)-2a(2)-Methylspiro[1-azabicyclo[2.2.2]octane-3,5a(2)-[1,3]oxathiolane]; (2R,2'R)-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]; cis-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]; Evoxac; AF-102B; (2R,2'R)-rel-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]; (2R,2'R)-Cevimeline
- 用途
- 盐酸西维美林（cevimeline hydrochloride）是选择性毒蕈碱受体激动剂，可促进涎腺分泌，用于治疗Sjögren综合征、放疗引起的口干症，也可作为预防龋齿的潜在药物（需系统临床研究证实）；已上市用于制备Evoxac胶囊（30mg）等制剂。
