- 英文名称
- 5-Bromo-2',3',5'-tri-O-acetyluridine
- 分子式
- C15H17BrN2O9
- 分子量
- 449.21
- 中文别名
- (2R,3R,4R,5R)-2-(乙酰氧基甲基)-5-(5-溴-2,4-二氧代-3,4-二氢嘧啶-1(2H)-基)四氢呋喃-3,4-二基 二乙酸酯; 5-溴尿苷 2',3',5'-三乙酸酯; (2R,3R,4R,5R)-2-(乙酰氧基甲基)-5-(5-溴-2,4-二氧亚基-3,4-二氢嘧啶-1(2H)-基)四氢呋喃-3,4-叉基二醋酸盐; (2R,3R,4R,5R)-2-(乙酰氧甲基)-5-(5-溴-2,4-二氧代-3,4-二氢嘧啶-1 (2H)-基)四氢呋喃-3,4-二基二乙酸盐; 5-溴-2',3',5'-三-O-乙酰尿苷; (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate; [3,4-diacetyloxy-5-(5-bromo-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate; 2',3',5'-Triacetyl-5-bromouridine; Uridine, 5-bromo-,2',3',5'-triacetate (9CI); 2',3',5'-Tri-O-acetyl-5-bromouridine; 5-BROMO-2',3',5'-TRI-O-ACETYLURIDINE; [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(5-bromo-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate; [(2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-(5-bromo-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methyl acetate; 5-bromouridine 2',3',5'-Triacetate; Uridine, 5-bromo-, 2',3',5'-triacetate
- 用途
- 5-溴尿苷 2',3',5'-三乙酸酯是嘌呤核苷类似物，具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。其抗癌机制依赖于抑制DNA合成，诱导细胞凋亡等。
