- 英文名称
- Argatroban Monohydrate
- 分子式
- C23H38N6O6S
- 分子量
- 526.65
- 中文别名
- (2R,4R)-1-((2S)-5-胍基-2-(3-甲基-1,2,3,4-四氢喹啉-8-磺胺基)戊酰基)-4-甲基哌啶-2-甲酸一水合物; (2R,4R)-1-[(2S)-5-(氨基亚氨甲基)氨基-1-氧代-2-[(3-甲基-1,2,3,4-四氢喹啉-8-基)磺酰胺基]戊烷]-4-甲基哌啶-2-甲酸; (2R,4R)-4-甲基-1-[N-[(3-甲基-1,2,3,4-四氢-8-喹啉基)磺酰]-L-精氨酰]-2-哌啶甲酸一水合物; 阿加曲班; 阿加曲班一水化合物; 阿加曲班单水合物; Argatroban; (2R,4R)-1-((2S)-5-Guanidino-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl)-4-methylpiperidine-2-carboxylic acid hydrate; (2R,4R)-1-{N-(Diaminomethylene)-N-[(3-methyl-1,2,3,4-tetrahydro-8-quinolinyl)sulfonyl]-L-ornithyl}-4-methyl-2-piperidinecarboxylic acid; 2-Piperidinecarboxylic acid, 1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-, hydrate (1:1); (2R,4R)-1-{N-(diaminomethylidene)-N-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonyl]-L-ornithyl}-4-methylpiperidine-2-carboxylic acid; (2R,4R)-4-Methyl-1-{N-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonyl]-L-arginyl}piperidine-2-carboxylic acid; (2R,4R)-4-Methyl-1-[N2-(3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-L-arginyl]-2-piperidinecarboxylic Acid; (2R,4R)-4-Methyl-1-{N-[(3-methyl-1,2,3,4-tetrahydro-8-quinolinyl)sulfonyl]-L-arginyl}-2-piperidinecarboxylic acid hydrate (1:1); Argatroban anhydrous; Argatroban (USAN:INN:BAN:JAN); Argatroban hydrate; Argatra; Exembol; Slonnon; Novastan; MDI-805; OM-805
- 用途
- 阿加曲班是人工合成抗凝血药，作为可逆竞争性凝血酶抑制剂，对凝血酶有强选择性抑制作用，抑制凝血酶引起的血小板聚集，用于预防和治疗血栓形成、肝素诱导的血栓栓塞、急性缺血性中风、心肌梗死溶栓辅助治疗、血透抗凝处理等；临床应用于周围动脉闭塞性疾病、急性脑血栓形成、抗凝血酶Ⅲ缺乏病人血透抗凝，以及经皮冠脉介入术病人治疗等。
