兰色染料; 蓝色染料; 汽巴蓝F3GA; 汽巴蓝3GA琼脂糖; 汽巴蓝/兰色染料; C.I.活性蓝2; 化合物T19049; Procion Blue HB; CIBRACONBLUEF3GA; Kayacion Blue A-B; C.I.REACTIVEBLUE2; Reactive blue 2 (C.I. 61211); 1-Amino-4-[[4-[[4-chloro-6-[[4-(sodiooxysulfonyl)phenyl]amino]-1,3,5-triazin-2-yl]amino]-3-(sodiooxysulfonyl)phenyl]amino]-9,10-dihydro-9,10-dioxo-2-anthracenesulfonic acid sodium salt
用途
- 生物活性
Procion Blue HB (Reactive Blue 2)是嘌呤能拮抗剂。
- 体外研究
Reactive Blue 2 is used as an ATP receptor antagonist and induces Ca
2+
oscillations in HeLa cells. Reactive Blue 2 enhances a Ca
2+
response to histamine that is linked to the PLC cascade. Reactive Blue 2 may activate the PLC cascade in an extracellular Ca
2+
-dependent manner and induce Ca
2+
oscillations. The application of Reactive Blue 2 increases K
+
secretion in a dose-dependent manner, and this increase is characterized as a peak followed by a partial relaxation to a steady-state. Reactive Blue 2 has antagonistic activities at P2Y4, and the antagonist potency at P2Y4 paralleled the potency of K+ secretion.The anthraquinone dye reactive blue 2 is found to be a potent inhibitor of a protein kinase isolated and purified from thylakoids. The mode of inhibition is noncompetitive, with a K
i
of 8 μM for the membrane-bound kinase, and 6 microM for the purified kinase. The inhibitor does not modify the substrate preference of the endogenous kinase and could be removed from the membrane by washing. Reactive blue 2 selectively inhibits responses mediated via the P2ypurinoceptor, at least within a limited concentration range. In preparations where the tone has been raised with noradrenaline, ATP and 2-methylthio ATP, but not α,β-methylene ATP, produce relaxations of the vessel. These relaxations are inhibited in the presence of reactive blue 2. Reactive blue 2, at concentrations of 0.3-10 μM blocks the ATP-induced oscillation in a concentration-dependent manner.
活性蓝 K-GL; 活性翠蓝K-GL; C.I.活性蓝14; Cibacron Brilliant Blue FC-4GP; Turqoise Blue K-GR; Reactive Blue Green K-GL; Reactive Brilliant Blue K-GL; Reactive Emerald Blue K-GL; Reactive Green Blue K-GL; C.I.Reactive Blue 14
活性蓝49(无盐规格); Reactive Blue HE3R; C.I. Reactive blue 49; Blue P-3R; Begative Blue P-3R; C.I.Reaction Blue 49; Chemifix Brilliant Blue P3R; Cibacron Blue P-3R; Everzol Blue P-3R; Rifacion Blue P-3R; Ostazin Blue H-3R; Kayacion Blue P-3R; Procion Blue H-3R
反应橙K-2RL; 活性黄棕K-GR; Procion Brown H-2G; Procion Orange Brown H-2G; C.I. Reactive brown 2; Tetrasodium 5-[(E)-{4-[(E)-{4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]-7-sulfonato-1-naphthyl}diazenyl]-2,5-dimethylphenyl}diazenyl]-1,3,6-naphthalenetrisulfonate
溶剂黑 RE; 溶剂黑B-10; 油溶黑401; C.I. Solvent Black 27; Black J 93; Duasyn Black A-IG-VP 280; Duasyn Black A-RG-VP 280; Neopen Black X 53; Neozapon Black RE; Neozapon Black X 51; Oleosol Fast Black RL; Vali Fast Black 3820; Bricosol Black NB; Zapon Black X 51; Lumaplast Black KB; Wei Qing Black 20; Banchaku Black Z 1-1500; Vali Fast Black 3840L; Savinyl Black NS; Varifast Black 3818; Vali Fast Black 3840; B 20
溶剂兰70; 溶剂蓝 BL; 油溶蓝501; C.I. Solvent Blue 70; Blue 2606; Duasyn Blue A-G-VP 279; Kayaset Blue K-FL; Neo Super Blue C 555; Neopen Blue 807; Neopen Blue 808; Neozapon Blue 807; Zapon Blue 807; Nubian Blue PA 4600; Orient Blue 2606; Bricosol Blue K 2GV; Oleosol Fast Blue GL; Orient Oil Blue 615; Oleosol Fast Blue ELN; Vali Fast Blue 2606; Oleosol Fast Blue EL; Spectra Blue FLE; Orasol Blue 855
溶剂红119; C.I.溶剂红 119; Benzamide, N-ethyl-N-methyl-3-(3-pyrrolidinyl)-, hydrochloride (1:1); Oil Fire Red G; C.I. Solvent Red 119; Neozapon Fire Red; Neozapon Fire Red G; Neozapon Red 355; Solvent Brown G; N-Ethyl-N-methyl-3-(3-pyrrolidinyl)benzamide hydrochloride (1:1)
