- 英文名称
- Ciwujianoside C3
- 分子式
- C53H86O21
- 分子量
- 1059.24
- 中文别名
- 刺五加皂苷C3; (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-(2S,3R,4S,5S,6R)-6-((((2R,3R,4R,5S,6R)-3,4-二羟基-6-(羟甲基)-5-(((2S,3R,4R,5R,6S)-3,4,5-三羟基-6-甲基四氢-2H-吡喃-2-基)氧基)四氢-2H-吡喃-2-基)氧基)甲基)-3,4,5-三羟基四氢-2H-吡喃-2-基 2,2,6a,6b,9,9,12a-七甲基-10-(((2S,3R,4S,5S)-3,4,5-三羟基四氢-2H-吡喃-2-基)氧基)-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-二十氢苉-4a-甲酸酯; (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-(2S,3R,4S,5S,6R)-6-((((2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl 2,2,6a,6b,9,9,12a-heptamethyl-10-(((2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate; oleanolic acid α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1->4)-O-β-gentiobiosyl ester; 3-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1-4)-O-β-D-glucopyranosyl-(1-6)-O-β-D-glucopyranosyl ester of oleanolic acid; 3-O-α-L-arabinopyranosyloleanolic acid 28-O-α-L-rhamnopyranosyl-(1->4)-β-D-gentiobiosyl ester; 3β-O-α-L-arabinopyranosylolean-12-en-28-O-α-L-rhamnopyranosyl-(1->4)-β-D-glucopyranosyl-(1->6)-β-D-glucopyranoside; oleanolic acid-3-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1-6)-O-β-D-glucopyranoside; Olean-12-en-28-oic acid, 3-(α-L-arabinopyranosyloxy)-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (3β)-
- 用途
- 生命科学；中草药成分；具有口服活性并可穿透血脑屏障，分离于刺五加叶子，具有抗炎作用并增强小鼠个体识别记忆力；体外实验中对RAW 264.7细胞无细胞毒性，抑制NO产生，降低p-ERK和p-JNK表达，剂量依赖性降低COX-2和iNOS mRNA表达；体内实验中口服给药0.5 mg/kg/天，17天可强化小鼠物体识别记忆；来源于刺五加干燥根茎，白色结晶粉末，可溶于甲醇、乙醇、DMSO等有机溶剂。
