- 英文名称
- (2S,3aS,6aS)-Benzyl octahydrocyclopenta[b]pyrrole-2-carboxylate hydrochloride
- 分子式
- C15H20ClNO2
- 分子量
- 281.78
- 中文别名
- S,S,S-2氮杂双环[3,3,0]辛烷-3-羟酸苄酯盐酸盐; 0]辛烷羧酸苄酯 盐酸盐; S)-2-氮杂双环[3; (S,S,S)-2-氮杂二环[3.3.0]辛烷-3-羧酸苄酯盐酸盐; (S,S,S)-2-氮杂双环[3.3.0]辛烷-3-羧酸苄酯盐酸; (S,S,S)-2-氮杂双环[3,3,0]辛烷羧酸苄酯 盐酸盐; (1S,3S,5S)-2-Azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochloride; (1S, 3S, 5S)-2-Azabicyclo[3,3,0]Octane-3-Carborylic Acid Benzyl Ester hydrochlor; (3S)–BENZYL CIS ENDO–2–AZABICYCLO [3.3.0] –OCTANE–3–CARBOXYLATE HYDROCHLORIDE; (3S)-BENZYL ENDO CIS-2-AZABICYCLO (3,3,0)-OCTANE HYDROCHLORIDE; BENZYL (S,S,S)-2-AZABICYCLO[3.3.0]OCTANE-3-CARBOXYLATE HYDROCHLORIDE; ENDO, CIS-2-AZABICYCLO [3.3.0] OCTANE-3-CARBOXYLIC ACID BENZYL ESTER HYDROCHLORIDE; CIS,ENDO-2-AZABICYCLO[3,3,0]OCTANE-3-CARBOXYLIC ACID BENZYL ESTER HYDROCHLORIDE; benzyl (2S,3aS,6aS)-1,2,3,3a,4,5,6,6a-octahydrocyclopenta[b]pyrrole-2-carboxylate,hydrochloride; (2S,3aS,6aS)-2-benzyl octahydrocyclopenta[b]pyrrole-2-carboxylate hydrochloride; (S,S,S)-2-azabicyclo<3,3,0>-octane-3-carboxylic acid benzylester hydrochloride; (S,S,S)-Octahydro-cyclopenta[b]pyrrole-2-carboxylic acid benzyl ester HCl; benzyl S,S,S-2-azabicyclo[3.3.0]octane-3-carboxylate hydrochloride; (2S,3aS,6aS)-octahydro-Cyclopenta[b]pyrrole-2-carboxylic acid,Benzyl Ester,HCl; 3.3.0>octane-3-carboxylic acid benzylester hydrochloride; (2S,3aS,6aS)-Benzyl octahydrocyclopenta[b]pyrrole-2-carboxylate hydrochloride; benzyl (2S,3AS,6AS)-octahydrocyclopenta[b]pyrrole-2-carboxylate hydrochloride
- 用途
- - 简介
(1S,3S,5S)-2-氮杂双环[3,3,0]辛烷-3-羧酸盐酸盐衍生物呈白色或灰白色结晶粉末状，其是合成雷米普利的关键中间体。
- 制备
以苯甲酰胺和丙酮酸乙酯为原料经缩合、加成反应，合成 2- 苯甲酰氨基 -3(2- 氧代环戊基 ) 丙酸乙酯。 在此基础上，再经水解环合、氢化， 可以得到雷米普利关键中间体 2- 氮杂双环[3.3.0] 辛烷 -3- 羧酸苄酯盐酸盐。其合成反应式如下图：
- 雷米普利中间体。
- 用于合成雷米普利药物
