- 英文名称
- Tamoxifen citrate
- 分子式
- C32H37NO8
- 分子量
- 563.64
- 中文别名
- 他莫昔芬柠檬酸盐; (Z)-N,N-二甲基-2-[4-(1,2-二苯基-1-丁烯基)苯氧基]-乙胺枸橼酸盐; 枸橼酸他莫昔芬(三苯氧胺); 枸缘酸他莫昔芬; (Z)-1-(对二甲基氨基乙氧基苯基)-1,2-二苯基-1-丁烯; 枸橼酸三苯氧胺; (Z)-[2-[4-(1,2-diphenylbut-1-enyl)phenoxy]ethyl]dimethylammonium dihydrogen 2-hydroxypropane-1,2,3-tricarboxylate; TAMOXIPHEN; Ethanamine, 2-4-(1Z)-1,2-diphenyl-1-butenylphenoxy-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1); TomixipheneCitrate; (Z)-1-(4-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene Citrate; (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine, citrate (1:1); Tamoxifen citrate salt; trans-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethylamine citrate; Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt); 2-{4-[(1Z)-1,2-Diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (1:1); Tamoxifen, citrate salt; Tamoxifen citrate; 2-{4-[(1Z)-1,2-Diphenyl-1-buten-1-yl]phenoxy}-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (1:1); 2-{4-[(1Z)-1,2-Diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanaminium hydrogen 2-hydroxypropane-1,2,3-tricarboxylate (1:2:1); 2-{4-[(1Z)-1,2-Diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (salt); Tamoxifen (Citrate)
- 用途
- 生命科学领域作为蛋白激酶C抑制剂，诱发人类恶性神经胶质瘤细胞系的细胞凋亡；医药领域用于治疗晚期、复发性乳腺癌和卵巢癌，还可用于乳腺癌预防、抗肿瘤及抗多药耐药性，以及心脏保护等。
