- 英文名称
- (5Z)-7-[(1R,2R,3S,5S)-2-{[(5-Hydroxy-1-benzothiophen-3-yl)carbonyl]amino}-6,6-dimethylbicyclo[3.1.1]hept-3-yl]-5-heptenoic acid
- 分子式
- C25H31NO4S
- 分子量
- 441.58
- 中文别名
- (5Z)-7-[(1R,2R,3S,5S)-2-[[(5-羟基苯并[B]噻酚-3-基)羰基]氨基]-6,6-二甲基双环[3.3.1]庚烷-3-基]-5-庚烯酸; 化合物T28651; S-5751; S 5751; S5751; (5Z)-7-((1R,2R,3S,5S)-2-(((5-Hydroxy-1-benzothien-3-yl)carbonyl)amino)-6,6-dimethylbicyclo(3.1.1)hept-3-yl)hept-5-enoic acid; 5-Heptenoic acid, 7-((1R,2R,3S,5S)-2-(((5-hydroxybenzo(b)thien-3-yl)carbonyl)amino)-6,6-dimethylbicyclo(3.1.1)hept-3-yl)-, (5Z)-; (Z)-7-((1R,2R,3R,5S)-2-((5-hydroxy1-benzothiophene-3-carbonyl)amino)-7,7-dimethyl-3-bicyclo(3.1.1)heptanyl)hept-5-enoic acid; (Z)-7-[(1R,2R,3S,5S)-2-[(5-Hydroxy-1-benzothiophene-3-carbonyl)amino]-6,6-dimethyl-3-bicyclo[3.1.1]heptanyl]hept-5-enoic acid; ((Z)-7-(1R,2R,3S,5S)-2-(5-hydroxybenzo(b)thiophen-3-ylcarbonylamino)-10-norpinan-3-yl)hept-5-enoic acid; (5Z)-7-{(1R,2R,3S,5S)-2-[(5-Hydroxy-1-benzothiophene-3-carbonyl)amino]-6,6-dimethylbicyclo[3.1.1]heptan-3-yl}hept-5-enoic acid; (Z)-7-((1R,2R,3S,5S)-2-(5-hydroxybenzo[b]thiophene-3-carboxamido)-6,6-dimethylbicyclo[3.1.1]heptan-3-yl)hept-5-enoic acid; (Z)-7-[(1R,2R,3S,5S)-2-[(5-hydroxybenzothiophene-3-carbonyl)amino]-6,6-dimethyl-norpinan-3-yl]hept-5-enoic acid; (Z)-7-{(1R,2R,3S,5S)-2-[(5-Hydroxy-benzo[b]thiophene-3-carbonyl)-amino]-6,6-dimethyl-bicyclo[3.1.1]hept-3-yl}-hept-5-enoic acid
- 用途
- 生命科学；概述
治疗哮喘药物S-5751中间体 是一种具有口服活性的前列腺素 DP 受体拮抗剂。S-5751 可抑制 PGD2 诱导的富血小板血浆 cAMP 生成，IC50 为 0.12 μM。S-5751 具有抗炎活性。S-5751 可用于哮喘的研究。
