- 英文名称
- Travoprost
- 分子式
- C26H35F3O6
- 分子量
- 500.55
- 中文别名
- 曲沃前列素; 曲伏前列腺素; 曲沃前列腺素; (Z)-异丙基 7-((1R,2R,3R,5S)-3,5-二羟基-2-((R,E)-3-羟基-4-(3-(三氟甲基)苯氧基)丁-1-烯-1-基)环戊基)庚-5-烯酸酯; (E)-7-[(1R,2S,3R,5S)-3,5-二羟基-2-[(E)-3-羟基-4-[3-(三氟甲基)苯氧基]丁-1-烯基]环戊基]庚-5-烯酸异丙醚; (+)-9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER; (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid 1-methyethyl ester; (+/-)-16-(M-TRIFLUOROMETHYLPHENOXY)TETRANORPROSTAGLANDIN F2; 15(S)-FLU-IPR; 15(S)-FLUPROSTENOL ISOPROPYL ESTER; 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)-; trevostaglandin; Fluprostenol isopropyl ester; Travaprost; AL 6221; Travatan; Travatan Z; Travo-Z; propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate; travoprostum; 15S-Travoprost; Trovoprost
- 用途
- 用于降低开角型青光眼或高眼压症患者升高的眼压。是一种选择性的前列腺素类受体激动剂，经眼部给药后被角膜水解酶水解成活性的游离酸，分布于眼组织中，结合后激活位于睫状肌和小梁细胞中的 PGFP 受体，通过增加葡萄膜巩膜途径房水外流来降低眼压。
