- 英文名称
- 5,6-trans-Vitamin D3
- 分子式
- C27H44O
- 分子量
- 384.64
- 中文别名
- 维生素D3杂质A; 胆钙化醇EP杂质A; 胆骨化醇杂质A; 胆钙化固醇EP杂质A; 维生素D3EP杂质A; 胆骨化醇杂质A(EP); 3Β,5E,7E-9,10-断胆甾-5,7,10[1P]-三烯-3-醇; 胆钙化醇杂质A; 维生素D3杂质1; Cholecalciferol Impurity A; (1S,3E)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol; (1S,3E)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-DiMethylhexyl]octahydro-7a-Methyl-4H-inden-4-ylidene]ethylidene]-4-Methylenecyclohexanol; (3β,5E,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol; (E,E)-9,10-Secocholesta-5,7,10(19)-trien-3β-ol; 5,6-trans-Cholecalciferol; Cholecalciferol Impurity A (5,6-trans-Cholecalciferol, 5,6-trans-Vitamin D3); (3.beta., 5E,7E)-9,10-Secocholesa-5,7,10[1p]-trien-3-ol; (3S,5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol; Cholecalciferol Impurity 1; Cholecalciferol EP Impurity A; (1S,Z)-3-((E)-2-((1R,7AR)-7a-methyl-1-((R)-6-methylheptan-2-yl)hexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexanol
- 用途
- 5,6-trans-Vitamin D3 (5,6-trans-Cholecalciferol;5,6-trans-Colecalciferol) 是维生素 D3 的光产物，代谢激活后能诱导细胞分化和癌细胞增殖。在体外研究中，通过测定其对 3H-胸苷掺入 DNA 的影响，发现 5,6-trans-vitamin D3 仅在 10(-6) M 时诱导显著抑制，其维生素 D 受体（VDR）的解离常数为 560 nM。
