- 英文名称
- Sodium ursodeoxycholate
- 分子式
- C24H39NaO4
- 分子量
- 414.55
- 中文别名
- (R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-二羟基-10,13-二甲基十六氢-1H-环戊二烯并[a]菲-17-基)戊酸钠; 熊去氧胆酸钠盐; Sodium (R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate; NaUDCh; SODIUM URSODEOXYCHOLATE HYDRATE; Cholan-24-oic acid, 3,7-dihydroxy-, sodium salt, (3α,5β,7β)- (1:1); Sodium (3α,5β,7β)-3,7-dihydroxycholan-24-oate; Ursodeoxycholic Acid (sodium salt); Cholan-24-oic acid, 3,7-dihydroxy-, MonosodiuM salt, (3a,5b,7b)-; (3alpha,5beta,7beta)-3,7-Dihydroxycholan-24-oic acid monosodium salt; Sodium ursodesoxycholate; UDCA Na; Ursodeoxycholate sodium; Ursodeoxycholic acid sodium
- 用途
- 是肠道屏障完整性的关键调节因子，对脂质代谢至关重要；作为信号分子，通过与胆汁酸激活的受体相互作用发挥作用，包括G蛋白偶联的胆汁酸受体5(TGR5，GPCR19)和法尼酯X受体(FXR)；可用于多种肝脏和胃肠道疾病的研究；具有口服活性
