- 英文名称
- rel-Sodium (3R,5S)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
- 分子式
- C33H34FN2NaO5
- 分子量
- 580.62
- 中文别名
- 阿托伐他汀钠; 阿托伐他汀(3R,5S)-异构体钠; 阿托伐他汀(3R,5S)-异构体钠盐; (3R,5S)-阿托伐他汀; (3R,5S)-阿托伐他汀钠盐; (3R,5S)-Atorvastatin Sodium Salt; sodium,(3R,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate; Sodium (3R,5S)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, sodium salt, (βR,δS)- (1:1); (AR,AS)-2-(4-Fluorophenyl)-A,A-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Sodium Salt; (3R,5S)-Atorvastatin (sodium); (3R,5S)-Atorvastatin sodium; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-ss,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, monosodium salt, (R*,S*)- (9CI); (3RS,5SR)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid sodium salt; Atorvastatin 10-Trans (Atorvastatin Impurity AT10); Sodium (3R,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate; (3R,5S)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxy-heptanoate; Atorvastatin Impurity AT10; (βR,δS)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrrole-1-heptanoic Acid SodiuM Salt
- 用途
- 化学合成；生物活性研究，(3R,5S)-Atorvastatin sodium 是 Atorvastatin 的杂质，Atorvastatin 是口服活性 HMG-CoA 还原酶抑制剂，可降低血脂，以 IC50 分别为 0.39 μM 和 2.39 μM 抑制人 SV-SMC 增殖和侵袭。
