- 英文名称
- N-(5-(N-(4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl)sulfamoyl)-4-methylthiazol-2-yl)acetamide
- 分子式
- C15H13F6N3O4S2
- 分子量
- 477.4
- 中文别名
- SR1001; 化合物SR1001; SR1001; SR-1001; SR 1001; N-(5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)sulphamoyl)-4-methylthiazol-2-yl)acetamide; N-(5-{[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxy-2-propanyl)phenyl]sulfamoyl}-4-methyl-1,3-thiazol-2-yl)acetamide; N-[5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide; N-(5-((4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)sulfamoyl)-4-methyl-1,3-thiazol-2-yl)acetamide; N-[4-Methyl-5-[[[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]amino]sulfonyl]-2-thiazolyl]-acetamide; N-[4-methyl-5-[[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]sulfamoyl]thiazol-2-yl]acetamide
- 用途
- SR1001 is a RORα inverse agonist, inhibits murine TH17 cell development by reducing IL-17A expression, suppresses autoimmune disease in mice by eliminating ROR target gene circadian patterns.
