- 英文名称
- (2'-Methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)(1'-methyl-6,7-dihydro-2H,5H-spiro[furo[2,3-f]indole-3,4'-piperidin]-5-yl)methanone hydrochloride
- 分子式
- C32H33ClN4O3
- 分子量
- 557.08
- 中文别名
- SB-224289盐酸盐; 化合物SB-224289盐酸盐; 化合物T12841; SB-224289 hydrochloride; SB 224289 hydrochloride; SB 224289A; SB-224289A; [4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]phenyl]-(1'-methylspiro[6,7-dihydro-2H-furo[2,3-f]indole-3,4'-piperidine]-5-yl)methanone,hydrochloride; (1'-Methyl-6,7-dihydro-5H-spiro[furo[2,3-f]indole-3,4'-piperidin]-5-yl)[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride (1:1); 1'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine] hydrochloride; Methanone, (6,7-dihydro-1'-methylspiro[2H-furo[2,3-f]indole-3(5H),4'-piperidin]-5-yl)[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]-, hydrochloride (1:1); (1'-Methyl-6,7-dihydro-5H-spiro[furo[2,3-f]indole-3,4'-piperidin]-5-yl)[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-4-biphenylyl]methanone hydrochloride (1:1)
- 用途
- 作为化学合成中间体；是选择性5-HT1B受体拮抗剂，具有抗焦虑作用，可用于研究5-HT1B受体相关的生理病理机制，在体内外实验中用于研究5-HT释放、受体活性及相关行为学影响，如增加焦虑样行为、调节运动活性、影响5-HT水平等。
