- 英文名称
- Ivermectin B1a
- 分子式
- C48H74O14
- 分子量
- 875.09
- 中文别名
- 依维菌素B1A; 伊维菌素杂质1; 伊佛霉素B1A; 伊维菌素H2B1A; 22,23-二氢阿维菌素 B1A; 22,23-dihydroavermectin B1a; Avermectin A1a, 5-O-demethyl-22,23-dihydro-; 22,23-Dihydro-5-O-demethylavermectin A1a; 5-O-Demethyl-22,23-dihydroavermectin A1a; Dihydroavermectin B1a; IvermectinH2B1a; Ivermectin Impurity 3; (2Ae,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17ar,20R,20ar,20bs)-20,20B-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-3',4',5',6,6',10,11,14,15,17,17A,20,20A,20B-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-o-(2,6-dideoxy-3-o-methyl-alpha-L-arabino-hexopyranosyl)-3-o-methyl-alpha-L-arabino-hexopyranoside
- 用途
- 伊维菌素B1a是伊维菌素（MK-933）的主要成分，伊维菌素是广谱抗寄生虫剂，也是应用于抗SARS-CoV-2/COVID-19的候选药物；伊维菌素由伊维菌素B1a（不低于80%）和伊维菌素B1b（不超过20%）组成的混合物，伊维菌素B1a在0.3μg/ml浓度下无活性，伊维菌素B1b在相同浓度下对蜗牛100%致死。
