- 英文名称
- Isopropyl (E)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoate
- 分子式
- C26H35F3O6
- 分子量
- 500.55
- 中文别名
- 5,6-反式-曲伏前列素; 5,6-TRANS曲沃前列素; 5,6-TRANS-曲伏前列素; 5,6-反式-曲伏前列素杂质; 曲伏前列素杂质29; 曲伏前列素杂质2(5,6-反式曲伏前列素); 5,6-trans Travoprost; Isopropyl (5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}cyclopentyl]-5-heptenoate; Isopropyl (5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-5-enoate; (5E,13E)-(9S,11R,15R)-9,11,15-Trihydroxy-(+)-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5,13-prostadienoic acid, isopropyl ester; 5,6-trans-Travoprost; Travoprost 5,6-trans isomer; Fluprostenol isopropyl ester; (+)-Travoprost; (5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; propan-2-yl (E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate; Travoprost Impurity 2; Isopropyl (9S,11R,15R)-9,11,15-trihydroxy-16-[3-(trifluoromethyl)phenoxy]-17,18,19,20-tetranor-5E,13E-prostadienoate
- 用途
- 生命科学；兽药；概述
5,6-反式-曲伏前列素 是 Travoprost (HY-B0584) 的异构体，可作为实验中的对照化合物。Travoprost (Fluprostenol isopropyl ester) 是一种异丙基酯前体，是一种高亲和力的，选择性的 FP 前列腺素全受体激动剂。Travoprost 有降眼压功效，有潜力应用于青光眼和眼高压。
