- 英文名称
- Heptelidic acid
- 分子式
- C15H20O5
- 分子量
- 280.32
- 中文别名
- (+)-萜烯七脂酸; 庚萜酸; (5aS,6R,9S,9aS)-1-Oxo-6-(propan-2-yl)-3,5a,6,7,8,9a-hexahydro-1H-spiro[2-benzoxepine-9,2'-oxirane]-4-carboxylic acid; (+)-heptelidic acid; 1,5a,6,7,8,9a-hexahydro-6-(1-methyl-ethyl)-1-oxo-spiro[2-benzoxepin-9(3H),2'oxirane]-4-carboxylic acid; koningic acid; (5aS,9S)-1,5a,6,7,8,9aα-Hexahydro-6β-(1-methylethyl)-1-oxospiro[2-benzoxepine-9(3H),2'-oxirane]-4-carboxylic acid; (5aS,9S)-1,5aβ,6,7,8,9aα-Hexahydro-6β-isopropyl-1-oxospiro[2-benzoxepine-9(3H),2'-oxirane]-4-carboxylic acid; Avocettin; Spiro[2-benzoxepin-9(3H),2'-oxirane]-4-carboxylic acid, 1,5a,6,7,8,9a-hexahydro-6-(1-methylethyl)-1-oxo-, (2'S,5aS,6R,9aS)-
- 用途
- 化学合成；作为倍半萜类抗生素；通过下调caspase抑制依托泊苷诱导的细胞凋亡；其类似物koningic acid是特异性GAPDH抑制剂，IC50为90μM
