- 英文名称
- Emodepside
- 分子式
- C60H90N6O14
- 分子量
- 1119.39
- 中文别名
- 哀默德斯; 艾德甙; 艾莫德丝; 艾莫德斯; (3S,6R,9S,12R,15S,18R,21S,24R)-3,9,15,21-四异丁基-4,6,10,16,18,22-六甲基-12,24-双(4-吗啉苄基)-1,7,13,19-四氧杂-4,10,16,22-四氮杂环二十四烷-2,5,8,11,14,17,20,23-八酮; Bay-44-4400; emodepsida; emodepsidum; BAY 44-4400; PF-1022-221; PF 1022-221; Cyclo((R)-lactoyl-N-methyl-L-leucyl-(R)-3-(p-morpholinophenyl)lactoyl-N-methyl-L-leucyl-(R)-lactoyl-N-methyl-L-leucyl-(R)-3-(p-morpholinophenyl)lactoyl-N-methyl-L-leucyl); (3S,6R,9S,12R,15S,18R,21S,24R)-4,6,10,16,18,22-hexamethyl-3,9,15,21-tetrakis(2-methylpropyl)-12,24-bis[(4-morpholin-4-ylphenyl)methyl]-1,7,13,19-tetraoxa-4,10,16,22-tetrazacyclotetracosane-2,5,8,11,14,17,20,23-octone; Cyclo((alphaR)-alpha-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(alphaR)-alpha-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl); Cyclo[(alphaR)-alpha-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(alphaR)-alpha-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl]; Cyclo[(αR)-α-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(αR)-α-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl]
- 用途
- Emodepside是一种具有广谱驱虫活性的环八肽，可激活Ca-dependent SLO-1-like K channels，在体外能抑制线虫的动作电位和钙电流，体内干扰线虫神经肌肉接头信号，抑制运动、摄食和繁殖，用于动物药物（FDA批准的动物药品活性成分）。
