- 英文名称
- 4-(3,5-Difluoropyridin-2-yl)-10-methyl-7-((methylsulfonyl)methyl)-11-oxo-3,4,10,11-tetrahydro-1H-1,4,10-triazadibenzo[cd,f]azulene-6-carboxylic acid
- 分子式
- C23H18F2N4O5S
- 分子量
- 500.47
- 中文别名
- PROTAC BRD4 ligand-1; 7-(3,5-二氟-2-吡啶基)-3,4,6,7-四氢-2-甲基-10-[(甲基磺酰基)甲基]-3-氧代-2H-2,4,7-三氮杂二苯并[CD,F]薁-9-羧酸; 7-(3,5-二氟-2-吡啶基)-2-甲基-10-[(甲砜基)甲基]-3-氧代-3,4,6,7-四氢-2H-吡啶并[3',4':6,7]吖庚因并[3,4,5-cd]异吲哚-9-甲酸; PROTAC BRD4 ligand-1; 2H-2,4,7-Triazadibenz[cd,f]azulene-9-carboxylic acid, 7-(3,5-difluoro-2-pyridinyl)-3,4,6,7-tetrahydro-2-methyl-10-[(methylsulfonyl)methyl]-3-oxo-; 8-(3,5-difluoropyridin-2-yl)-15-methyl-4-(methylsulfonylmethyl)-14-oxo-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaene-5-carboxylic acid; PROTAC BRD4 ligand 1; PROTAC BRD4 ligand1; PROTAC BRD-4 ligand-1; 7-(3,5-difluoropyridin-2-yl)-2-methyl-10-((methylsulfonyl)methyl)-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulene-9-carboxylic acid; 7-(3,5-Difluoro-2-pyridyl)-2-methyl-10-[(methylsulfonyl)methyl]-3-oxo-3,4,6,7-tetrahydro-2H-pyrido[3',4':6,7]azepino[3,4,5-cd]isoindole-9-carboxylic Acid
- 用途
- 是一种有效的BET抑制剂，是靶向BRD4蛋白的配体，可用于合成PROTAC GNE-987 (HY-129937A)
