- 英文名称
- Calcobutrol
- 分子式
- C18H32CaN4O9
- 分子量
- 488.55
- 中文别名
- rel-2,2'-(7-(羧甲基)-10-((2R,3S)-1,3,4-三羟基丁-2-基)-1,4,7,10-四氮杂环十二烷-1,4-二基)二乙酸钙盐; REL-10-[(1R,2S)-2,3-二羟基-1-(羟甲基)丙基]-1,4,7,10-四氮杂环十二烷-1,4,7-三乙酸钙盐; 降骨脂醇; 钙布醇; REL-1,4,7,10-四氮杂环十二烷-1,4,7-三乙酸,10-[(1R,2S)-2,3-二羟基-1-(羟甲基)丙基]-,钙盐(1:1); rel-Calcium 2,2'-(7-(carboxymethyl)-10-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4-diyl)diacetate; 1,4,7,10-Tetraazacyclododecane-1,4,7-triaceticacid, 10-[(1R,2S)-2,3-dihydroxy-1-(hydroxymethyl)propyl]-, calcium salt (1:1), rel-; calcium 2,2'-(7-(carboxymethyl)-10-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4-diyl)diacetate; calcium,2-[4-(carboxylatomethyl)-10-(carboxymethyl)-7-(1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetrazacyclododec-1-yl]acetate; Calcobutrol [INN]; Calciumbutrol; Calcium hydrogen 10-((1RS,2SR)-2,3-dihydroxy-1-(hydroxymethyl)propyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetate; CALCOBUTROLUM; 1,4,7,10-TETRAAZACYCLODODECANE-1,4,7-TRIACETIC ACID, 10-(2,3-DIHYDROXY-1-(HYDROXYMETHYL)PROPYL)-, CALCIUM SALT (1:1), (R*,S*)-(+-)-
- 用途
- 考布曲钙是钆布醇制剂（溶液剂）的辅料之一，解决了钆布醇制剂中游离钆的释放问题。钆布醇由钆（III）与大环配体10-(2,3-二羟基-1-(羟基甲基)丙基)-1,4,7,10-四氮杂环十二烷-1,4,7-三乙酸构成非离子络合物，考布曲钙作为其钙盐形式，可能参与该络合物的稳定化过程。
