- 英文名称
- 5a,6-Anhydrotetracycline
- 分子式
- C22H22N2O7
- 分子量
- 426.42
- 中文别名
- 莱姆霉素EP杂质C; 四环素EP杂质C; 化合物 Anhydrotetracycline; 金霉素杂质10(金霉素EP杂质J); 脱水四环素; (4S,4aS,12aS)-4-(二甲基氨基)-3,10,11,12a-四羟基-6-甲基-1,12-二氧代-1,4,4a,5,12,12a-六氢并四苯-2-甲酰胺; (2Z,4S,4aS,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino-10,11,12a-trihydroxy-6-methyl-4a,5-dihydro-4H-tetracene-1,3,12-trione; (1S)-1α-(Dimethylamino)-2,4aα,6,7-tetrahydroxy-4,5-dioxo-11-methyl-1,4a,12,12aα-tetrahydronaphthacene-3-carboxamide; (4S)-4β-Dimethylamino-1,4,4aβ,5,12,12a-hexahydro-3,10,11,12aβ-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide; (4S)-Anhydrotetracycline; 3,10,11,12aβ-Tetrahydroxy-4β-(dimethylamino)-6-methyl-1,12-dioxo-1,4,4aβ,5,12,12a-hexahydronaphthacene-2-carboxamide; (4R)-4α-Dimethylamino-1,4,4aβ,5,12,12a-hexahydro-3,10,11,12aβ-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide; 4-Epianhydrotetracycline; Anhydrotetracyclin; (4S,4aS,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-6-methyl-3,12-dioxo-4a,5-dihydro-4H-tetracene-2-carboxamide; (4S,4aS,12aS)-4-(Dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide
- 用途
- Anhydrotetracycline 是四环素失活酶小分子抑制剂，对抗四环素类抗生素的酶降解。Anhydrotetracycline 能够在表达四环素破坏酶的全细胞大肠杆菌中拯救四环素活性。
