- 英文名称
- monacolin J
- 分子式
- C19H28O4
- 分子量
- 320.42
- 中文别名
- (4R,6R)-4-羟基-6-(2-((1S,2S,6R,8S,8aR)-8-羟基-2,6-二甲基-1,2,6,7,8,8a-六氢萘-1-基)乙基)四氢-2H-吡喃-2-酮; 辛伐他汀内酯二醇; 洛伐他汀二醇内酯; 辛伐他汀杂质; 洛伐他汀内酯二醇; 6(R)-[2-(8(S)-羟基]-2(S),6(R)-二甲基-1,2,6,7,8,8A(R)-六氢-1(S)-萘基]乙基-4(R)-羟基-3,4,5,6-四氢-2H-吡喃-2-酮; 洛伐他汀酮内酯; 辛伐他汀杂质10; 辛伐他汀杂质H (EP); 辛伐他汀EP杂质H; (4R,6R)-4-Hydroxy-6-(2-((1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl)tetrahydro-2H-pyran-2-one; 6(R)-[2-(8(S)-Hydroxy]-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one; Antibiotic MB 530A; (4R,6R)-4-Hydroxy-6-{2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydro-1-naphthalenyl]ethyl}tetrahydro-2H-pyran-2-one; (4R,6R)-6-[2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl]-4-hydroxyoxan-2-one; Lovastatin diol lactone; Simvastatin EP Impurity H; MONACOLIN J; SiMvastatin Lactone Diol; Lovastatin Lactone Diol; Lovastatin Impurity 8
- 用途
- 化学合成；作为合成心血管药物辛伐他汀的主要前体；是胆固醇合成抑制剂，能够抑制HMG-CoA reductase的活性
