- 英文名称
- Nocloprost
- 分子式
- C22H37ClO4
- 分子量
- 400.98
- 中文别名
- 化合物Nocloprost; 化合物T33710; (5Z,9β,11α,13E,15R)-9-Chloro-11,15-dihydroxy-16,16-dimethylprosta-5,13-dien-1-oic acid; (5Z,9b,11a,13E,15R)-9-Chloro-11,15-dihydroxy-16,16-dimethylprosta-5,13-dien-1-oic Acid; (5Z,13E)-(9R,11R,15R)-9-chloro-11,15-dihydroxy-16,16-dimethyl-5,13-prostadienoic acid; SH-475; (Z)-7-((1R,2R,3R,5R)-5-Chloro-3-hydroxy-2-((E)-(3R)-3-hydroxy-4,4-dimethyl-1-octenyl)cyclopentyl)-5-heptenoic acid; (Z)-7-[(1R,2R,3R,5R)-5-chloro-2-hydroxy-2-[(E)-(3R)-3-hydroxy-4,4-dimethyl-1-octenyl]cyclopentyl]-5-heptenoic acid; (5Z,13E,15R)-9β-Chloro-11α,15-dihydroxy-16,16-dimethylprosta-5,13-dien-1-oic acid; Prosta-5,13-dien-1-oic acid, 9-chloro-11,15-dihydroxy-16,16-dimethyl-, (5Z,9β,11α,13E,15R)-; Prosta-5,13-dien-1-oicacid, 9-chloro-11,15-dihydroxy-16,16-dimethyl-, (5Z,9b,11a,13E,15R)-
- 用途
- 诺氯前列素是口服有效的前列腺素E2(PGE2)类似物，是EP1和EP3受体激动剂；抑制诱发的[3H]ACh释放；具有胃保护和溃疡愈合特性；加速大鼠慢性胃溃疡的愈合并增强粘膜生长。
