- 英文名称
- Somatostatin-25
- 分子式
- C127H191N37O34S3
- 分子量
- 2876.3
- 中文别名
- 化合物Somatostatin-25; SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS(二硫键:CYS14-CYS25); H-SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH(二硫键:CYS14-CYS25); 内源性神经肽激素; 内源性神经肽激素SOMATOSTATIN-25; 生长激素抑制素SOMATOSTATIN25; L-Seryl-L-asparaginyl-L-prolyl-L-alanyl-L-methionyl-L-alanyl-L-prolyl-L-arginyl-L-α-glutamyl-L-arginyl-L-lysyl-L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-13,25,28-tribenzyl-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide; SNPAMAPRERKAGCKNFFWKTFTSC; SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS; SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS(DISULFIDE BRIDGE: CYS14-CYS25); H-SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH; Somatostatin-25 (sheep)
- 用途
- 作为内源性神经肽激素，抑制生长激素分泌；在体外系统中，0.1 pM-1 nM浓度可显著抑制生长激素分泌，效果比十四肽强3-14倍；0.1 nM-1 pM浓度可抑制前列腺素2（PGE2）诱导的生长激素分泌；对催乳素分泌无影响
