- 英文名称
- Triciribine phosphate
- 分子式
- C13H17N6O7P
- 分子量
- 400.28
- 中文别名
- ((2R,3S,4R,5R)-5-(3-氨基-5-甲基-1,4,5,6,8-五氮杂苊烯-1(5H)-基)-3,4-二羟基四氢呋喃-2-基)甲基磷酸酯; 三环核苷磷酸盐; 曲西立滨磷酸盐; ((2R,3S,4R,5R)-5-(3-Amino-5-methyl-1,4,5,6,8-pentaazaacenaphthylen-1(5H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate; 5-Methyl-1-(5-O-phosphono-b-D-ribofuranosyl)-1,5-dihydro-1,4,5,6,8-pentaazaacenaphthylen-3-amine; 5-Methyl-1-(5-O-phosphono-β-D-ribofuranosyl)-1,5-dihydro-1,4,5,6,8-pentaazaacenaphthylen-3-amine; Pentaazaacenaphthylene-5' phosphate ester; 3-Amino-1,5-dihydro-5-methyl-1-b-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylene 5'-(Dihydrogen Phosphate); Phosphate Salt of Tricyclic Nucleoside; Triciribine phosphate (USAN); VQD-002; TCN-P; 1-(5-O-Phosphono-β-D-ribofuranosyl)-5-methyl-1,5-dihydro-1,4,5,6,8-pentaazaacenaphthylene-3-amine; 1,5-Dihydro-5-methyl-1-(5-O-phosphono-β-D-ribofuranosyl)-1,4,5,6,8-pentaazaacenaphthylene-3-amine; NSC-280594; Triciribine 5'-phosphate; 1,4,5,6,8-Pentaazaacenaphthylene-3-amino-1,5-dihydro-5-methyl-1-beta-D-ribofuranosyl 5'-monophosphate; VQD 002
- 用途
- 通过变构机制抑制酰胺磷酸核糖基转移酶，影响嘌呤从头生物合成的第一个关键步骤；抑制IMP脱氢酶，这是鸟苷核苷酸合成的第一个关键步骤；不影响连接酶活性
