- 英文名称
- trans-1,1'-(Cyclohexane-1,4-diyl)bis(N-(2-chlorobenzyl)methanamine) dihydrochloride
- 分子式
- C22H30Cl4N2
- 分子量
- 464.3
- 中文别名
- 化合物AY 9944; AY 9944; trans-1,4-bis(chlorobenzylaminomethyl)-cyclohexane dihydrochloride; N,N'-[1,4-Cyclohexanediylbis(methylene)]bis[1-(2-chlorophenyl)methanamine] dihydrochloride; N,N'-[Cyclohexane-1,4-diylbis(methylene)]bis[1-(2-chlorophenyl)methanamine] dihydrochloride; 1,4-bis(2-chlorobenzylaminomethyl)cyclohexane dihydrochloride; 1,4-Cyclohexanediylbis[N-(2-chlorobenzyl)methanamine] dihydrochloride; trans-1,4-Cyclohexanediylbis[N-(2-chlorobenzyl)methanamine] dihydrochloride; trans-N,N'-bis((2-chlorophenyl)methyl)-1,4-Cyclohexanedimethanamine dihydrochloride; 1,4-Cyclohexanedimethanamine, N,N-bis[(2-chlorophenyl)methyl]-, hydrochloride (1:2); 1,4-Cyclohexanedimethanamine, N,N-bis[(2-chlorophenyl)methyl]-, trans-, hydrochloride (1:2); 1,4-cyclohexanebis(methylamine),n,n’-bis(2-chlorobenzyl)-,dihydrochloride; 4-cyclohexanebis(methylamine),n,n’-bis(o-chlorobenzyl)-dihydrochloride; trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexanedihydrochloride; N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine dihydrochloride; AY9944
- 用途
- 特异的胆固醇生物合成抑制剂，抑制7-脱氢胆固醇Δ7-还原酶（IC50=13 nM），引起胆固醇不足和7DHC积累；高剂量下抑制固醇Δ7-Δ8异构酶，导致胆固醇8-en-3β-ol积累；口服-小鼠LD50:155毫克/公斤；可燃，燃烧产生有毒氮氧化物和氯化物烟雾；库房通风低温干燥，与食品原料分开存放；灭火剂为干粉、泡沫、沙土、二氧化碳、雾状水
