- 英文名称
- phomoxanthone A
- 分子式
- C38H38O16
- 分子量
- 750.7
- 中文别名
- 化合物 Phomoxanthone A; (5R,5'R,6R,6'R,10aR,10'aR)-10a,10'a-bis(acetoxymethyl)-1,1',9,9'-tetrahydroxy-6,6'-dimethyl-8,8'-dioxo-5,5',7,7',8,8',10a,10'a-octahydro-6H,6'H-[4,4'-bixanthene]-5,5'-diyl diacetate; (5R,5'R,6R,6'R,10aR,10'aR)-5,5'-Bis(acetyloxy)-10a,10'a-bis[(acetyloxy)methyl]-5,5',6,6',7,7',10a,10'a-octahydro-1,1',8,8'-tetrahydroxy-6,6'-dimethyl-[4,4'-bi-9H-xanthene]-9,9'-dione
- 用途
- 对恶性疟原虫Plasmodium falciparum（K1，耐多药菌株，IC50为0.11 µg/mL）和结核分枝杆菌Mycobacterium tuberculosis（H37Ra菌株，MIC为0.50 µg/mL）具有抗疟和抗结核活性；在KB、BC-1和Vero细胞中表现出细胞毒性，IC50分别为0.99、0.51和1.4 µg/mL
