- 英文名称
- Arnicolide D
- 分子式
- C19H24O5
- 分子量
- 332.39
- 中文别名
- 山金草内酯D; (3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-三甲基-2,5-二氧代-2,3,3a,4,4a,5,7a,8,9,9a-十氢环戊并环庚烯并[6,5-b]呋喃-4-基 甲基丙烯酸酯; (3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-Trimethyl-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl methacrylate; 11alpha,13-dihydrohelenalinmethacrylate; 11,13-Dihydrohelenalin methacrylate; [(1S,3aR,5R,5aR,8aR,9S,9aR)-1,5,8a-trimethyl-2,8-dioxo-3a,4,5,5a,9,9a-hexahydro-1H-azuleno[6,5-b]furan-9-yl] 2-methylprop-2-enoate; (3aR)-4,4a,7aα,8,9,9aα-Hexahydro-4α-(methacryloyloxy)-3β,4aβ,8α-trimethylazuleno[6,5-b]furan-2,5(3H,3aαH)-dione; 2-Methylpropenoic acid [(3S)-2,3,3aα,4,4a,5,7aα,8,9,9aα-decahydro-3β,4aβ,8α-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4α-yl] ester; Plenolin methacrylate; 2-Propenoic acid, 2-methyl-, (3S,3aR,4S,4aR,7aR,8R,9aR)-2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-yl ester
- 用途
- 生命科学领域应用;中草药成分;作为从石胡荽中分离的倍半萜内酯,调节细胞周期,激活caspase信号通路,抑制PI3K/AKT/mTOR和STAT3信号通路,以剂量和时间依赖性方式显著抑制鼻咽癌细胞生长
