- 英文名称
- 2,3',4,4',5-Pentachlorobiphenyl
- 分子式
- C12H5Cl5
- 分子量
- 326.43
- 中文别名
- 2,3',4,4',5-五氯联苯; 氯联苯118; 多氯联苯118; 化合物T33896; 2,3',4,4',5-Pentachloro-1,1'-biphenyl; 2,3',4,4',5-pentachloro-bipheny; 2,4,5,3',4'-Pentachlorobiphenyl; 3,4,2',4',5'-Pentachlorobiphenyl; Biphenyl, 2,3',4,4',5-pentachloro-; 1,2,4-trichloro-5-(3,4-dichlorophenyl)benzene; 1,1'-Biphenyl,2,3',4,4',5-pentachloro; PCB 118; 2,3',4,4',5-PCB
- 用途
- 概述
PenCB (PCB 118) could induce pyroptosis by priming and activating NFκB-dependent NLRP3 inflammasome. PCB 118 induces oxidative stress and pyroptosis are dependent on Aryl hydrocarbon receptor (AhR) activation and subsequent cytochrome P450 1A1 upregulation.
