- 英文名称
- Asperulosidic acid
- 分子式
- C18H24O12
- 分子量
- 432.38
- 中文别名
- 车叶草酸; 车叶草甙酸; 异叶马鞭草酸; (1S,4AS,5S,7aS)-7-(乙酰氧基甲基)-5-羟基-1-((3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-基)氧基)-1,4a,5,7a-四氢环戊烷[c]吡喃-4-羧酸; asuperlosidic acid; (1S,4aS,5S,7aS)-7-Acetoxymethyl-5-hydroxy-1-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-1,4a,5,7a-tetrahydro-cyclopenta[c]pyran-4-carboxylic acid; Asperulosidinsaeure; (1S,4aS,5S,7aS)-7-[(Acetyloxy)methyl]-1-(beta-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxycyclopenta[c]pyran-4-carboxylic acid; Cyclopenta[c]pyran-4-carboxylic acid, 7-[(acetyloxy)methyl]-1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-, (1S,4aS,5S,7aS)-
- 用途
- 作为中草药成分，具有抗肿瘤、抗病毒、抗氧化、抗畸变、抗炎等活性；通过抑制NF-κB和MAPK信号通路抑制炎性细胞因子释放发挥抗炎作用；在体外研究中可下调LPS诱导的RAW 264.7细胞中TNF-α和IL-6的mRNA水平，降低IκB-α和Erk1/2磷酸化水平。
