- 英文名称
- AZD-0284
- 分子式
- C21H18F6N2O5S
- 分子量
- 524.43
- 中文别名
- AZD-0284; 化合物AZD-0284; Azd-0284; AZD0284; Azd 0284; (R)-2-Acetyl-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-5-(methylsulfonyl)isoindoline-1-carboxamide; (1R)-2-acetyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-5-methylsulfonyl-1,3-dihydroisoindole-1-carboxamide; (1~{R})-2-ethanoyl-~{N}-[4-[1,1,1,3,3,3-hexakis(fluoranyl)-2-oxidanyl-propan-2-yl]phenyl]-5-methylsulfonyl-1,3-dihydroisoindole-1-carboxamide; 1H-Isoindole-1-carboxamide, 2-acetyl-2,3-dihydro-5-(methylsulfonyl)-N-(4-(2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl)phenyl)-, (1R)-; (1R)-2-acetyl-5-methylsulfonyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoindoline-1-carboxamide; (1R)-2-acetyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-5-methanesulfonyl-2,3-dihydro-1H-isoindole-1-carboxamide
- 用途
- 化学合成；作为人类核视黄酸相关孤儿受体(RORɣ)的反向激动剂，具有治疗斑块性寻常型银屑病和呼吸道疾病的潜力。
