- 英文名称
- Desmethylbellidifolin
- 分子式
- C13H8O6
- 分子量
- 260.2
- 中文别名
- 去甲基龙胆呫吨酮酚; 去甲基雏叶龙胆酮; 去甲基雏菊叶龙胆口山酮; 去甲基雏菊叶龙胆素; 1,3,5,8-四羟基呫酮; 1,3,5,8-四羟基山酮; 1,3,5,8-Tetrahydroxy-9H-xanthene-9-one; 1,3,5,8-Tetrahydroxy-9-xanthenone; 1,3,5,8-Tetrahydroxy-9H-xanthen-9-one; 1,3,5,8-Tetrahydroxyxanthane; Desmethylbellidifoline; Norbellidifodin; Bellidin; Xanthen-9-one,1,3,5,8-tetrahydroxy; norbellidifolin; 1,3,5,8-tetrahydroxyxanthone; Desmethybellidifolin; 1,3,5,8-tetrahydroxy-xanthen-9-one; 1,3,5,8-tetrahydroxyxanthen-9-one
- 用途
- - 生物活性
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) 是一种从 Gentianella acuta 中提取的天然黄酮。1,3,5,8-Tetrahydroxyxanthone 具有镇痉作用和抗炎活性。
- 体外研究
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) attenuates lipopolysaccharide-induced nitric oxide release and proinflammatory cytokine expression in RAW264.7 cells.
- 体内研究
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin; orally; 5, 10, 20 mg/kg; 12 days) can inhibit trinitrobenzenesulfonic acid (TNBS)-induced ulcerative colitis (UC), reducing inflammatory response and alleviate colon muscle spasm.
- 化学性质
黄色结晶粉末，可溶于甲醇、乙醇、DMSO等有机溶剂。
- 去甲基雏叶龙胆酮具有清热解毒，抗氧活性，致突变活性的作用。
