- 英文名称
- Dalfopristin
- 分子式
- C34H50N4O9S
- 分子量
- 690.85
- 中文别名
- 达福司汀; 达福普丁; (3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(二乙氨基)乙基]磺酰基]-8,9,14,15,24,25,26,26a-八氢-14-羟基-4,12-二甲基-3-(1-甲基乙基)-3H-21,18-腈-1H,22H-吡咯并[2,1-c][1,8,4,19]二氧杂二氮杂环二十四碳四烯-1,7,16,22(4H,17H)-四酮; (1(2)Z,3(2)S,3(3)R,6R,7R,17S)-3(3)-((2-(二乙氨基)乙基)磺酰基)-17-羟基-6-异丙基-7,15-二甲基-5-氧杂-11-氮杂-1(4,2)-噁唑-3(1,2)-吡咯烷酰基二十碳六烯酸-8,13,15-三烯-2,4,10,19-四酮; Dalfopristine; Dalfopristina; Dalfopristinum; RP 54476; RP-54476; RP54476; 26-(2-diethylaminoethyl)sulfonylpristamycin IIB; Virginiamycin M1, 26-((2-(diethylamino)ethyl)sulfonyl)-26,27-dihydro-,(26R,27S)-; (3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(Diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone; (6R,7S,10R,11R,12E,17E,19E,21S)-6-[2-(diethylamino)ethylsulfonyl]-21-hydroxy-11,19-dimethyl-10-propan-2-yl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),12,17,19,25(28)-pentaene-2,8,14,23-tetrone
- 用途
- 主要用于治疗成人致命性耐万古霉素屎肠球菌(VREF)菌血症相关性感染、耐甲氧西林金黄色葡萄球菌(MRSA)及化脓性链球菌引起的皮肤及软组织感染；其活性范围包括革兰氏阳性病原体，及对其他种类的抗菌化合物具有抗性的病原体。
