- 英文名称
- Tiotropium Bromide Impurity
- 分子式
- C9H16BrNO2
- 分子量
- 250.13
- 中文别名
- 噻托溴铵EP杂质H (异构体混合物); 噻托溴铵杂质; 溴化噻托溴铵EP杂质H; 噻托溴铵EP杂质H溴化物; (2S,3aR,5S,6S,6aS)-6-羟基-4,4-二甲基六氢-2H-2,5-甲基糠醛[3,2-B]吡咯-4-溴化铵; 噻托溴铵EP杂质溴化氢; Tiotropium Bromide EP Impurity H (Mixture of Enantiomers); (2RS,3aSR,5RS,6RS,6aRS)-6-Hydroxy-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium bromide; 2,5-Methano-2H-furo[3,2-b]pyrrolium, hexahydro-6-hydroxy-4,4-dimethyl-, bromide (1:1), (2R,3aS,5R,6R,6aR)-rel-; Tiotropium Bromide EP Impurity H; Tiotropium bromide Impurity 17; Tiotropium Bromide EP Impurity H Bromide; Rel-(2R,3aS,5R,6R,6aR)-6-hydroxy-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium bromide; (2S,3aR,5S,6S,6aS)-6-Hydroxy-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium bromide
- 用途
- 噻托溴铵是一种抗胆碱能药物，也是长效抗毒蕈碱药物，对毒蕈碱受体亚型M1至M5有相似亲合性，通过抑制呼吸道平滑肌M3受体舒张支气管，用于慢性阻塞性肺病(COPD)治疗；噻托溴铵杂质为其生产或储存过程产生的杂质。
