- 英文名称
- Pinokalant
- 分子式
- C41H49ClN2O9
- 分子量
- 749.289
- 中文别名
- 化合物PINOKALANT; 2-(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)-2-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]acetamide; loe 908; 3,4-Dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-1-isoquinolineacetamidehydrochloride; 1-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-; Loe-908; Pinokalant [INN]; pinokalantum; (+-)-3,4-Dihydro-6,7-dimethoxy-alpha-phenyl-N,N-bis(2,3,4-trimethoxyphenethyl)-1-isoquinolineacetamide; 2-(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)-2-phenyl-N,N-bis(2,3,4-trimethoxyphenethyl)acetamide; (3,4-Dihydro-6,7-dimethoxyisoquinoline-1-gamma-1)-2-phenyl-N,N-di(2-(2,3,4-trimethoxyphenyl)ethyl)acetamide; DA-65043; (+/-)-3,4-DIHYDRO-6,7-DIMETHOXY-.ALPHA.-PHENYL-N,N-BIS(2,3,4-TRIMETHOXYPHENETHYL)-1-ISOQUINOLINEACETAMIDE; (r,s)-(3,4-dihydro-6,7-dimethoxy-isoquinoline-1-yl)-2-phenyl-n,n-di-[2-(2,3,4-trimethoxyphenyl)ethyl]-acetamide; 1-ISOQUINOLINEACETAMIDE, 3,4-DIHYDRO-6,7-DIMETHOXY-.ALPHA.-PHENYL-N,N-BIS(2-(2,3,4-TRIMETHOXYPHENYL)ETHYL)-, (+/-)-
- 用途
- Pinokalant 是一种广谱阳离子通道抑制剂，可减少大鼠大脑中动脉闭塞后急性期磁共振图像上的病变大小，改善缺血半影区的代谢和电生理状态，减少皮质梗死体积，具有研究脑卒中的潜力。
