- 英文名称
- Cytochalasin B
- 分子式
- C29H37NO5
- 分子量
- 479.61
- 中文别名
- 松胞素B; 细胞分裂抑素B; 细胞松驰素B; (3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-16-苄基-5,13-二羟基-9,15-二甲基-14-亚甲基-6,7,8,9,10,12a,13,14,15,15a,16,17-十二氢-2H-[1]氧杂环十四并[2,3-d]异吲哚-2,18(5H)-二酮; Phomin; (3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-16-Benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylene-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione; (3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione; cytochalasin; (7S),(20R)-Dihydroxy-16(R)-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13(E),21(E)-triene-1,23-dione; (E,E)-16-BENZYL-6,7,8,9,10,12A,13,14,15,15A,16,17-DODECAHYDRO-5,13-DIHYDROXY-9,15-DIMETHYL-14-METHYLENE-2H-OXACYCLOTETRADE[2,3-D]ISOINDOLE-2,18(5H)-DIONE
- 用途
- 作为细胞松弛素B，是一种细胞可渗透的真菌毒素，能与肌动蛋白丝的正端结合，抑制F-肌动蛋白的聚合与解聚，干扰细胞移动、吞噬作用、胞质分裂等活动；用于细胞骨架研究，在体外对多种肿瘤细胞系有抑制作用，体内可延长携带P388/ADR白血病的Balb/c小鼠生存期。
