- 英文名称
- 4',5'-Didehydro-5'-deoxyuridine
- 分子式
- C9H10N2O5
- 分子量
- 226.19
- 中文别名
- 4',5'-二脱氢-5'-脱氧尿苷; 1-(5-脱氧-β-D-赤式-戊-4-烯呋喃糖基)尿嘧啶; 1-((2R,3R,4S)-3,4-Dihydroxy-5-methylenetetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(5-Deoxy-β-D-erythro-pento-4-enofuranosyl)uracil; 4',5'-didehydro-5'-deoxy-uridine; 1-((2R,3R,4S)-3,4-dihydroxy-5-methylene-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione; 5'-deoxyuridin-4'-ene; 1-(5-deoxy-β-D-erythro-pent-4-enofuranosyl)uracil; 1-(5'-Deoxy-β-D-erythro-pent-4'-enofuranosyl)uracil; Uridine, 4',5'-didehydro-5'-deoxy-; 1-[(2R,3R,4S)-3,4-dihydroxy-5-methylideneoxolan-2-yl]pyrimidine-2,4-dione; 4,5-Didehydro-5-deoxyuridine; 1-[(2R,3R,4S)-3,4-dihydroxy-5-methylideneoxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione; 1-((2R,3R,4S)-3,4-dihydroxy-5-methylene-tetrahydrofuran-2-yl)pyrimidine-2,4-dione; 1-[(2R,3R,4S)-3,4-dihydroxy-5-methylidenetetrahydro-2-furyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
- 用途
- 化学合成；作为嘌呤核苷类似物，具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤，其抗癌机制依赖于抑制DNA合成，诱导细胞凋亡。
