- 英文名称
- N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite
- 分子式
- C46H50F2N5O8P
- 分子量
- 869.89
- 中文别名
- 吉西他滨亚磷酰胺单体; (2R,3R,5R)-5-(4-苯甲酰胺基-2-氧代嘧啶-1(2H)-基)-2-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-4,4-二氟四氢呋喃-3-基 (2-氰基乙基)二异丙基亚磷酰胺; N4-苯甲酰基-5'-O-[二(4-甲氧基苯基)苯基甲基]-2',2'-二氟胞苷-3'-[2-氰基乙基二异丙基氨基亚磷酸酯]; 二异丙基亚磷酰胺[(2R,3R,5R)-5-[4-苯甲酰氨基-2-氧代嘧啶-1(2H)-基]-2-[[双(4-甲氧基苯基)(苯基)甲氧基]甲基]-4,4-二氟四氢-3-呋喃基]酯[(2-氰基乙基)]酯; (2R,3R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4,4-difluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMTr-2',2'-difluoro-dC(Bz)-3'-CED-phosphoramidite; N-[1-[(2R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3,3-difluorooxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide; 5'-O-DMT-N4-Benzoyl-2',2'-difluoro-2'-deoxycytidine 3'-CE phosphoramidite; DMTr-2',2'-difluoro-dC(Bz)-3'-CED-phosphoramidite; N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite; (2R,3R,5R)-5-[4-Benzamido-2-oxopyrimidin-1(2H)-yl]-2-[[bis(4-methoxyphenyl)(phenyl)methoxy]methyl]-4,4-difluorotetrahydro-3-furyl (2-Cyanoethyl) Diisopropylphosphoramidite; N-[1-[(2R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-3,3-difluoro-tetrahydrofuran-2-yl]-2-oxo-pyrimidin-4-yl]benzamide; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluoro-2'-deoxycytidine; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2',2'-difluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluoro-2'-deoxycytidine 3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite; N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluoro-2'-deoxycytidine-3'-cyanoethyl Phosphoramidite
- 用途
- N-苯甲酰基-2-脱氧-5-O-DMT-2',2'-二氟胞苷3-CE亚磷酰胺是一种嘌呤核苷类似物，具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤，其抗癌机制依赖于抑制DNA合成，诱导细胞凋亡。
